The development of stents requires greater investment in the medical device industry

Release date: 2007-11-12

The development of the stent requires a greater investment in the medical device industry at the European Conference on Cardiovascular and Interventional Radiology. There is a speech named after Andreas Gruntzig. At the annual meeting in September 2007, Andreas Gruntzig was a speaker in Texas, USA. Julio Palmaz, a professor at the University Medical Science Center, gave his opinion on the development of stents before the end of the speech. He urged the industry to align with the electronics industry in the investment in stent development. He said that since 2001, the development of new vascular stents has generally lacked characteristics, mainly due to insufficient investment in the medical device industry.
In the development of the world's first listed stent, Palmaz is invincible. He said that we need to develop a basic technology that can improve the consistent healing effect of the entire vascular system. The only way to achieve this goal is to invest a lot of money into this business.
What he calls the basic technology is the ability to solve the problem that endothelial cells can not root on the entire scaffold surface at the molecular level. He explained that on the surface of the stainless steel scaffold material, the gap between chromium and iron causes endothelial cells to appear. Irregular and unpredictable seed behavior. He said that this may be the cause of the 30% restenosis rate of bare metal coronary stents.
The effect of the drug stent after placement in small blood vessels is satisfactory. This is because the inflammatory reaction and hyperplasia of small blood vessels can be resolved by the drug stent, but in the large blood vessels, the effect of the drug stent is not exerted, which is due to The lack of complete healing of large blood vessels, or vascular tissue reactions, leads to the expulsion and leakage of endothelial cells.
He believes that this basic technology should improve the healing properties of the entire vascular system. This can be achieved by using nano-sized non-adhesive basic materials for metal stents, which can promote the growth and reproduction of endothelial cells. Another possible method is to use a molecularly imprinted polymer material that captures protein ligands that promote healing of blood vessels on the surface of the stent.
In his speech, he asked, where did the idea of ​​developing the basic technology of this bracket come from? He said that this idea is everywhere, but in order to realize this concept, it requires money, it takes time, and it needs enthusiasm.
That is why, before ending this speech, he called on the medical and clinical community to call for the medical device industry to need more research and development investment.
He said that the only way to create a miracle is to pay!
——Shanghai Medical Device Industry Association

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