New antibodies can withstand 99% HIV variants
September 25, 2017 Source: Technology Daily
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];According to the latest issue of Science, the National Institutes of Health and the pharmaceutical company Sanofi, using a new antibody jointly developed by genetic engineering technology, can attack 99% of HIV (HIV) strains and prevent primates. Animals are infected. The antibody has been successfully tested in monkeys and human clinical trials will be launched next year.
The reason why humans are difficult to cure after HIV infection is because the HIV virus has extraordinary variability. The HIV virus variant in a single patient is equivalent to the type of virus in the global influenza epidemic, and the patient's immune system must fight against a huge number of HIV variants.
A small number of HIV patients develop antibodies with broad neutralizing ability that attack HIV basic substances and kill large numbers of HIV variants after many years of infection. Researchers have been trying to use this widely neutralized antibody as a preferred method to treat HIV or prevent infection. In the latest study, scientists combined three widely neutralizing antibodies to create a more powerful "triple-specific" antibody that attacks three key parts of the HIV virus against 99% of HIV variants.
The researchers' experiments on 24 monkeys showed that monkeys injected with new antibodies were reinjected with HIV, and none of the monkeys showed signs of infection. Sanofi chief scientist Gary Naber said that only very low concentrations of this antibody produce more powerful and broader effects than any of the best naturally occurring antibodies that can withstand 90% of HIV variants.
Professor Linde Gale Baker, president of the International AIDS Society, said the research was an exciting breakthrough. Dr. Anthony Fitch, director of the National Institute of Allergy and Infectious Diseases, said that combining antibodies that bind HIV at different sites or overcoming HIV defense mechanisms and achieving optimal antibody-based treatment and prevention . (Feng Weidong)
The material of this scar sticker consists of a silicone gel, usually skin-colored in appearance, and is indicated for scar recovery treatment and prevention.It is prohibited to be used before the wound has healed. Allergic reaction to silicone rubber material is prohibited. Car scar stickers prevent the scars from proliferation effectively, soften and smooth the scars effectively. Scar car sticker relieve pruritus and pain quickly. Scar removing sticker Moisturizing and breathable, realistick scars sticker is reusable and washable; Comfortable, ultra-thin fabric,Safe and effective; scar patch sticker without latex and drug free; Before use this product, clean the scar area or wipe it with a cotton swab dipped in 75% alcohol to disinfect it before use, and let it dry. Open the package, remove lion king scar stickers and cut the scar patch to the right size. Remove the backing film and stick the sticky side on the scar. Blue scar silicone sticker can be continuously pasted on the scar surface until the stickiness disappears.
Scar Stickers,Fake Wound Stickers,Silicone Gel Dressing,Silicone Gel Scar Dressing
Henan Maidingkang Medical Technology Co.,Ltd , https://www.mdkmedical.com