OFweek medical technology, according to Reuters data show that China cardiovascular disease patients, about 290 million people, an average of every five adults there is one person suffering from cardiovascular disease. Moreover, about 3.5 million people die of various cardiovascular diseases every year in China. On average, 2 out of every 5 deaths are due to cardiovascular disease, and 1 person is killed every 10 seconds. Cardiovascular disease has gradually become a resident of China. The main cause of death.
On November 14th, the “OFweek 2017 (2nd) China Medical Technology Conference†hosted by OFweek China High-Tech Industry Portal and the High-Tech Association, and held by OFweek Medical Technology Network, was held in Shenzhen. In this context, in the keynote speech “Breakthrough on Biomarker Research and Personalized Drug Guidance for Accurate Medical Treatment of Cardiovascular Diseasesâ€, Li Guanglei, Assistant Executive Dean of the Institute of Precision Soil Medicine, South University of Science and Technology, shared the results of cardiovascular disease research in detail. And measures for prevention and control.
Li Guanglei, Assistant Executive Dean, Institute of Precision Soil Medicine, South University of Science and Technology
Cardiovascular disease challenges
At present, the main treatments for cardiovascular diseases are drug therapy and interventional therapy. The drug treatment method requires medication for life, which is difficult to cure. Interventional therapy includes radiofrequency ablation, balloon dilation, stent implantation, etc. Can temporarily relieve the disease, and can not completely cure. The above two methods, from the essence, do not cure the symptoms, and have not completely solved the problem of cardiovascular disease.
Regarding the challenges faced in the treatment of cardiovascular diseases, Dean Li Guanglei said: "Some of the cardiovascular disease attacks and prevention of chronic diseases such as chronic diseases are difficult to solve."
At the same time, Li Guanglei made the following simple summary of the current causes of cardiovascular disease and prevention and treatment.
She said: "With the continuous development of science and technology, in the future, we can prevent the occurrence of cardiovascular diseases by means of accurate risk prediction and detection of cardiovascular diseases for healthy and sub-health populations, and personalized medication guidance for patients. ."
Genetic risk screening
According to a survey of cardiovascular diseases, the main causes of cardiovascular disease are environmental factors and genetic factors. Among them, environmental factors are the external thrust of disease occurrence and progress, and genetic factors are the internal motivations for disease occurrence and progress. There are uncertainties in environmental factors, and the chances of cardiovascular disease can be reduced by cultivating good living habits. Genetic factors are derived from heredity, although they cannot be changed, but genetic testing can predict and analyze the incidence of cardiovascular disease in advance, and then take preventive measures.
Taking coronary heart disease research as an example, by analyzing the plasma and urine metabolite data of the collected patients with coronary heart disease, the difference between the same data of coronary heart disease or normal people was compared, and the drug most suitable for the individual of the gene was selected. According to the survey, the drug that is most suitable for the individual gene can reach 75% of the patient's effect, and if the drug is used on an individual who is not suitable for his genotype, its efficacy is only 10%. This shows the importance of genetic testing for the treatment of cardiovascular disease.
Biomarker study of coronary heart disease
Personalized medication guidance
Li Guanglei said: "Because of the difference in genes, the individual's response to drugs will be different. When taking the same kind of drugs, some people have obvious effects and little side effects; some people are not only ineffective, but also have toxic side effects and even allergies. Through advanced Gene SNP typing detection technology, mapping and mapping a cardiovascular drug gene information map, providing individualized drug guidance programs for 17 kinds of common cardiovascular drugs in 5 clinical categories, while achieving the best therapeutic effect, the largest Reduce the adverse effects of the drug."
Finally, Li Guanglei said that in the future, genetic testing and personalized drug use may become the most effective means of cardiovascular disease prevention and treatment.
For more details, please pay attention to the follow-up reports of OFweek Medical Technology Network!
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