Release date: 2017-07-27
The National Institutes of Health announced on the 24th that a South African child diagnosed with HIV after birth has achieved a "functional cure" after receiving antiretroviral drugs supported by the institution in infancy. In 8 and a half years, no medical treatment was received, and the virus in the body was still suppressed.
The "functional cure" of AIDS means that after the HIV-infected person stops treatment, although there is still a small amount of virus in the body, the virus is completely inhibited and difficult to detect by conventional methods, and various functions of the body are normal.
The National Institutes of Health said in a statement on the same day that in 2007, the child was diagnosed with HIV after 32 days of birth. The child subsequently participated in a clinical trial supported by the agency and received antiretroviral therapy at 2 months of age for a total of 40 weeks.
The statement said that after receiving treatment, the child had no detectable HIV in his blood. When the child was 9 and a half years old, the researchers found only HIV in their body that was bound to a small number of immune cells. This virus was in an incubation period and was completely inhibited.
The statement states that the child does not have genetic characteristics associated with spontaneous control of HIV, so receiving 40 weeks of antiretroviral therapy should be the key to a "functional cure."
Two AIDS children had previously achieved a “functional cure†after receiving antiretroviral drugs. One of them was a "Mississippi baby" from the United States. He was treated 30 hours after he was born in 2010. After 18 months, he was interrupted for a reason. The "functional cure" lasted for 27 months, and his condition relapsed. The other is a French child born in 1996 who is treated between 3 months and 6 years of age and remains “functionally cured†until the age of 18.
“We still need to further study how to mitigate the long-term effects of HIV on infected children,†said Anthony Foch, director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. “But this new case adds to our hopes. , that is, short-term treatment of AIDS children in infancy, we may exempt them from the burden of lifelong treatment and the health consequences of long-term immune activation associated with AIDS."
Source: Xinhua News Agency
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