The effect and function of diterpenoid

Ditex grass (scientific name: Corydalis bungeana Turcz.), nicknamed: Aster (Beijing Flora, Inner Mongolia Flora), Peng's Aster (Beijing Botany), Bridite Terracotta (Northeast Medicinal Plant Map). Herbs are perennial, 10-30 cm tall. The roots are fine and straight, with few branches and yellowish brown. The stems are weak and more branched from the base to the sides, with edges, grayish green, light hair or sparsely growing pilose. Basal leaves clustered, basal leaves alternate, stalked; adaptable, warm and slightly cool climate. Cold, afraid of drought. Poor soil requirements, clay, loam, sandy loam can be planted. Distribution of Guangdong, Guangxi, Zhejiang, Jiangxi and other places. With dry grass for medicinal purposes, there is the effectiveness of heat and detoxification, attending bloated, hemorrhoids, Fengreganmao, bronchitis, hepatitis, enteritis embolism.

Sexuality

1 "Liaoning commonly used Chinese herbal medicine manual": "bitter, cold."

2 "Plateau Herbal Treatment Handbook": "The cold, bitter taste, small poison; into the heart, spleen."

地丁草

Function Indications

Detoxification. Governance fever, fever, irritability, flu, infectious hepatitis, nephritis, sputum, mumps, acne and other purulent infections.

1 "Liaoning Common Chinese Herbal Medicine Handbook": "Clearing away heat and toxic substances. Treating bloated, lymph node tuberculosis."

2 "Handbook of Hebei Traditional Chinese Medicine": "Treatment of acute infectious hepatitis."

3 "Plateau Herbal Treatment Handbook": "Anti-inflammatory detoxification. Treatment of jaundice hepatitis, fever irritability."

Dosage

Oral: Decoction, 5 to 15 grams (fresh 50 to 100 grams); or wolfberry juice. External use: apply.

Pharmacological effects

Using human embryonic kidney primary monolayer epithelial tissue culture, its water extract (1:80) has an inhibitory effect on herpes simplex virus and can delay the cytopathogenic effect of orphan virus. The whole plant is made into Kudidi injection. The active ingredient is mainly alkaloids. Antibacterial action in vitro, inhibition of Streptococcus A, Pneumococcus, Catascus, Shigella, Escherichia coli, Pseudomonas aeruginosa (test tube method); also have effect on staphylococcus (gold and white), and X. Agar plate punching method). The primary monolayer epithelial cells of human embryonic kidney were also used for tissue culture. The 1:10 bitter-budding injection showed no inhibition on polio (vaccine strain) Aike 18, Coxsackie B1, and adenovirus type III; There was no inhibition in the clotting unit influenza A. Jingke 68-1 strain (1:160), but there was suppression of the parainfluenza Sendai strain. The toxicity was very small. Mice were injected intraperitoneally with approximately 120 times the amount of humans (8 ml/kg), and no death was observed. With 10 ml/kg, there were 3/10 deaths. Kudi Ding injection intravenous injection of anesthetized cats and dogs, showing a temporary decrease in blood pressure, recovery within half a minute; with isolated frog heart perfusion, inhibit the role of the heart.

chemical composition

Contains more than 10 alkaloids. From there, four different alkaloids were obtained: Bitterbuprecin, B, C, and B (temporary name). It also contains coumarin lactones, steroidal saponins, phenolic substances, neutral resins, and volatile oils.

Distributed in Gansu, Inner Mongolia, Jiangsu, Shaanxi, Shanxi, Shandong, Hebei, Liaoning, Jilin, Heilongjiang, Sichuan and other places.

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