Release date: 2015-01-29
A recent study by the University of Queen Mary at the University of London, published in The Lancet, found that a revolutionary blood pressure lowering device can significantly lower a patient's blood pressure compared to conventional medications. .
The device, invented by ROX Medical, called the Coupler, is a paper clip-sized implant that is inserted between the artery and vein above the thigh, and the entire procedure lasts for 40 minutes under local anesthesia.
The researchers used a randomized, blinded endpoint clinical trial in which subjects had resistant hypertension, at least for three drug treatments.
To compare the effects of Coupler with conventional medications, 44 of 83 subjects underwent Coupler therapy. Patients receiving Unionr therapy have significantly lower blood pressure and are persistent. In addition, complications of hypertension are also reduced.
Coupler therapy also works well for patients who are not responding to permanent denervation, a new method of treating hypertension, suggesting that Coupler can target different mechanisms of hypertension. However, patients who have not previously been treated with renal denervation can achieve the same level of blood pressure after Coupler therapy, or even better. In addition, this new device is completely revocable, direct, and painless compared to the renal denervation.
Dr. Melvin Lobo of Queen Mary's College, University of London, who led the study, said: "This is a new approach to treating high blood pressure. Existing drugs focus on hormone and nervous system regulation. Some new treatments, such as renal denervation alone Focused on the renal nervous system. Coupler is an effective mechanism to target blood circulation. Coupler also stressed the importance of arteriosclerosis. Arteriosclerosis is the main cause of the formation of resistant hypertension, Coupler successfully and safely solved this Obstacles. Once the Coupler is implanted, the effect is very significant."
Treating high blood pressure with a Coupler will be a new option for doctors and patients in the future, especially when those conventional therapies fail. In addition, during the study, five people in the control group were admitted to the hospital due to a high blood pressure crisis, and this was not the case in the Coupler group.
Of course, Coupler has the same side effects as other therapies. Chest swelling was observed in 29% of patients treated with Coupler, indicating that another procedure is needed to solve this problem, usually by implanting a stent in the vein.
Dr. Melvin Lobo concluded: “Hypertension is very dangerous and can lead to stroke, heart disease and chronic kidney disease. When the drug does not work, we must find a better treatment. Coupler is moving towards a new treatment. An important step. It is too early to apply the Coupler to clinical care; we need more research to identify the effects of the Coupler, better understand its safety and explore how it works in the body. However, at the beginning of this year we have started the International Registry, which shows that as long as regular treatments do not provide a blood pressure lowering effect for patients, we will continue to offer Coupler treatment options for uncontrolled high blood pressure patients. â€
Source: biodiscover
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